Dates: August 11-13, 2016
Location: Oregon State University, Corvallis Oregon USA
Chairs: Ryan Mehl & Jason Chin
GCE Pre-Conference Workshop Dates: August 5 (10:00 am start) -August 10 5pm (finish).
Keynote Speakers
David Tirrell, California Institute of Technology, USA
Kensaku Sakamoto, Riken, Japan
Foundational Technology
David Tirrell, California Institute of Technology, USA
Kensaku Sakamoto, Riken, Japan
Kaihang Wang, MRC Cambridge, England
Abhishek Chatterjee, Boston College, USA
Bioorthogonal Chemistry
Jen Prescher, University of California, Irvine, USA
Kathrin Lang, Technische Universität München, Germany
Qing Lin, University of Buffalo, USA
Imaging and Control
Edward Lemke, European Molecular Biology Laboratory, Germany
Peng Chen, Peking University, China
Kai Johnsson, École Polytechnique Fédérale de Lausanne, Switzerland
Exploring Protein Structure And Function
Satpal Virdee, University of Dundee, Scotland, UK
Ben Davis, Oxford University, UK
James Petersson, University of Pennsylvania, USA
Schedule
Schedule as of 8/9/2016
Thursday, August 11, 2016
| 2:00 pm – 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:00 pm – 7:15 pm | Welcome / Introductory Comments by GCE Site Staff |
| 7:15 pm – 7:40 pm | Welcome from the Chairs and conference tasks. |
| 7:40 pm – 9:30 pm | Keynote Session: Foundational technology |
| Discussion Leader: Kimberly Beatty, Oregon Health & Science Univeristy | |
| 7:40 pm – 8:20 pm | Thursday 1: David Tirrell, California Institute of Technology
Some Recent Experiments in Protein Engineering and Proteomic Analysis |
| 8:20 pm – 8:30 pm | Discussion |
| 8:30 pm – 8:45 pm | Thursday 2 Poster talk 1 John Perona, Portland State University
“Improved Incorporation of Noncanonical Amino Acids by an Engineered tRNA(Tyr) Suppressor” |
| 8:45 pm – 8:50 pm | Discussion |
| 9:00 pm – 10:30 pm | Poster Setup and Discussion |
Friday, August 12, 2016
| 7:30 am – 8:30 am | Breakfast |
| 9:00 am – 12:30 pm | Session 1: Exploring Protein Structure And Function |
| Discussion Leader: Chris Ahern, University of Iowa | |
| 9:00 am – 9:30 am | Friday 1 Satpal Virdee, University of Dundee
Protein Engineering Through Genetic Code Expansion |
| 9:30 am – 9:40 am | Discussion |
| 9:40 am – 10:10 am | Friday 2 Ben Davis, Oxford University
Towards Post-translational Mutagenesis |
| 10:10 am – 10:20 am | Discussion |
| 10:20 am – 10:50 am | Coffee Break |
| 10:50 am – 11:20 am | Friday 3 James Petersson, University of Pennsylvania
Multiple labeling of proteins with side chain and backbone probes |
| 11:20 am – 11:30 am | Discussion |
| 11:30 am – 11:45 am | Friday 4 Joe DiDonato, Cleveland Clinic
Using Genetic Code Expansion to determine the functional consequences of posttranslational modifications observed in atherosclerosis on protective proteins |
| 11:45 am – 11:50 am | Discussion |
| 11:50 am – 12:05 pm | Friday 5 Poster Talk 2 Anna-Carin Carlsson, Colorado State University
“Engineering Halogen Bonds to Affect Protein Stabilization”. |
| 12:05 pm – 12:10 pm | Discussion |
| 12:10 pm – 12:25 pm | Friday 6 Poster Talk 3 Shixin Ye,
“Minimal optical switches uncover dynamic allostery of neuronal receptors”. |
| 12:25 pm – 12:30 pm | Discussion |
| 12:30 pm | GCE Conference Photo |
| 12:40 pm | Lunch |
| 1:30 pm – 4:00 pm | Free Time |
| 4:00 pm – 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm – 9:30 pm | Session 2: Bioorthogonal Chemistry |
| Discussion Leader: Karl Schilke, Oregon State University | |
| 7:30 pm – 8:00 pm | Friday 7 Jenn Prescher, University of California
Expanding the bioorthogonal toolkit |
| 8:00 pm – 8:10 pm | Discussion |
| 8:10 pm – 8:40 pm | Friday 8 Qing Lin, University of Buffalo
Reactivity-Based Chemical Tools for Biomedical |
| 8:40 pm – 8:50 pm | Discussion |
| 8:50 pm – 9:20 pm | Friday 9 Kathrin Lang, Technische Universität München
Expanding the Genetic Code – Chemistry in Living Systems |
| 9:20 pm – 9:30 pm | Discussion |
| 9:30 pm – 10:30 pm | Poster Session |
Saturday, August 13, 2016
| 7:30 am – 8:30 am | Breakfast |
| 9:00 am – 12:30 pm | Session 3: Imaging and Control |
| Discussion Leader: Parisa Hosseinzadeh, University of Washington | |
| 9:00 am – 9:30 am | Saturday 1 Edward Lemke, European Molecular Biology Laboratory
Tools to decode plasticity in the dark proteome |
| 9:30 am – 9:40 am | Discussion |
| 9:40 am – 9:55 pm | Saturday 2 Poster talk 4 Jan Grunewald, Genomics Institute of the Novartis Research Foundation
“The Unique Chemical Reactivity of Pyrroline-Carboxy-Lysine and Its Implications For Protein Labeling and Purification” |
| 9:55 pm – 10:00 pm | Discussion |
| 10:00 pm – 10:15 pm | Saturday 3 Poster talk 5 Ken-ichi Haruna, Frontier Research Labs. Institute For Innovation Ajinomoto Co., Inc.
“New principle of protein engineering based on the biosynthesis utilizing codon reassignments in Escherichia coli“. |
| 10:15 pm – 10:20 pm | Discussion |
| 10:20 am – 10:50 am | Coffee Break |
| 10:50 am – 11:20 am | Saturday 4 Peng Chen, Peking University
Chemical-decaging mediated protein activation in living systems |
| 11:20 am – 11:30 am | Discussion |
| 11:30 am – 11:45 am | Saturday 5 Kaihang Wang, MRC Cambridge
An orthogonal genetic code |
| 11:45 am – 11:50 am | Discussion |
| 11:50 am – 12:05 pm | Saturday 6 Poster talk 6 Charles E. Melancon III, University of New Mexico
“Development and Application of an Expanded Streptomyces Genetic Code” |
| 12:05 pm – 12:10 pm | Discussion |
| 12:10 pm – 12:25 pm | Saturday 7 Poster talk 7 Simone Costa, Duke University
“Non-canonical Amino Acids in Elastin-like Polypeptides for Small Molecule Conjugation”. |
| 12:25 pm – 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm – 4:00 pm | Free Time |
| 4:00 pm – 6:00 pm | Poster Session |
| 6:00 pm – 7:15 pm | Dinner |
| 7:15 pm – 8:00 | GCE Future Planning Session |
| 8:00 pm – 9:40 pm | Session 4: Foundational technology |
| Discussion Leader: Ryan Mehl, Oregon State University | |
| 8:10 pm – 8:40 pm | Saturday 8 Abhishek Chatterjee, Boston College
A universal platform for genetic code expansion |
| 8:40 pm – 8:50 pm | Discussion |
| 8:50 pm – 9:30 pm | Saturday 9 Kensaku Sakamoto, Riken
Expanded genetic codes in mammalian cells, codon reassignments in E. coli, and their applications |
| 9:30 pm – 9:40 pm | Discussion |
| 9:40 pm – 10:30 pm | Poster Session |
Sponsors
